The Systems Laboratory focuses on enabling the use of the latest Information and Communication Technologies (ICTs) in CEU's core areas of expertise. Special emphasis is placed on modeling environmental and social systems and promoting the use of geospatial technologies. Syslab develops and delivers graduate courses and workshops on Geographic Information Systems (GIS) and remote sensing, tailored to the needs of various CEU departments and units.

In addition, Syslab conducts regular in-service training sessions for practitioners and professionals on applying ICTs in various fields, including disaster management, water security, and biodiversity conservation, among others. To stay at the forefront of technological advancements and provide participants with cutting-edge insights, Syslab collaborates with global leaders in geospatial technologies, such as the UN Office for Outer Space Affairs, the UN Development Program, the European Commission's Joint Research Center, Esri, and Google. For more details, see the ISEPEI Project.

In 2012, Syslab launched the Spatial Mapping and Analysis Research Group  to create a platform for the CEU community to collaborate on applying geospatial technologies in cross-departmental and multidisciplinary research.